Cortagen – Powder

Description

Cortagen – Research Peptide | 20mg

Cortagen is a synthetic tetrapeptide originally isolated from the larger neuropeptide complex Cortexin. It has been studied in various preclinical models focusing on neural regeneration, mitochondrial gene regulation, and brain injury response.

Research Highlights:

• Neural Regeneration
  In rodent models of sciatic nerve transection, Cortagen administration was associated with a 27% increase in axonal growth and a 40% improvement in conduction velocity during nerve fiber regeneration.
• Brain Injury Models
  Cortagen demonstrated positive outcomes in traumatic brain injury (TBI) models, performing comparably or better than Cerebrolysin under specific dosing conditions. Some studies noted that Cerebrolysin required higher doses to achieve similar results.
• Cortical & Serotonin Modulation
  Data suggests Cortagen may influence cortical neuron activation, serotonin synthesis, and lipid peroxidation, pointing to potential effects on central nervous system regulation under experimental conditions.
• Mitochondrial Gene Regulation
  Cortagen has been observed to affect expression of mitochondrial genes such as 16S, COX-3, and ND5, which are involved in protein synthesis and electron transport chain function — particularly relevant to cardiac tissue, which has high mitochondrial density.

Specifications:

• CAS: Unknown
• Molar Mass: 430.17 g/mol
• Sequence: Ala–Glu–Asp–Pro
• Purity: ≥99%
• Form: Lyophilized powder
• Amount: 20mg per vial
• Storage: Store in the refrigerator for short-term use, tightly sealed and protected from heat, light, and moisture. For long-term storage, keep in a freezer.

Further Context:
Cortexin, the parent compound of Cortagen, has been evaluated in broader research models addressing neurological and cardiovascular functions. Cortagen’s isolated role is under continued investigation to better understand its individual biological activity.